Remote Patient Monitoring (RPM) is reshaping healthcare delivery by enabling providers to track physiological data—such as blood pressure, blood glucose, heart rate, and oxygen saturation—outside traditional clinical settings. With CMS reimbursement codes making RPM financially viable, healthcare practices are adopting platforms that improve patient outcomes while generating new revenue streams. Below, we rank the top five RPM platforms, with Actuvi leading the way for its unique dual RPM/RTM capabilities, AI-powered patient engagement, and revenue optimization.
1. Actuvi
Website: https://www.actuvi.com/
Why It’s #1
Actuvi stands apart as the only platform that seamlessly combines Remote Patient Monitoring (RPM) and Remote Therapeutic Monitoring (RTM) in a single, unified solution. This dual capability allows healthcare practices to monitor both physiological data (blood pressure, glucose, weight, SpO2) and non-physiological data (pain levels, therapy adherence, patient-reported outcomes) within one workflow. Actuvi’s FDA-compliant Software-as-a-Medical Device (SaMD) platform integrates with major EHR and EMR platforms, supporting billing for both RPM and RTM CPT codes to maximize revenue potential—up to $180/patient/month per monitoring type. (*Note that the same patient can’t be billed for both at the same time).
For RPM specifically, Actuvi allows patients to use their existing smart devices to log vitals directly in the mobile app, ensuring equitable access for all patients regardless of their device access. Data from blood pressure monitors, smart scales, and fitness trackers syncs automatically through Apple Health and Google Fit integration, or patients can manually log readings directly in the app.
What truly sets Actuvi apart is Actuvi Intelligence—AI agents that actively work to maximize patient compliance without burdening clinical staff. When patients miss their monitoring tasks on the app, Actuvi’s AI automatically reaches out via text messaging or WhatsApp to provide reminders and even administer assessments directly through these channels. This ensures consistent patient engagement and data collection.
The platform uses gamification to drive adherence, allowing patients to track their progress through streaks and achievement metrics. Actuvi’s intelligent alert system uses customizable thresholds for each patient based on clinical protocols, automatically notifying staff when intervention is necessary. The patient-facing mobile app provides a single point of access where patients can view their health trends, complete assessments, communicate with care teams, and receive automated reminders.
For patients who cannot use a mobile app independently, Actuvi’s Guardian Access feature allows designated caregivers to monitor and report data on their behalf, ensuring truly inclusive care delivery. Actuvi’s white-glove onboarding process designs custom monitoring protocols for your specialty, trains your staff, and provides ongoing technical support. The platform also tracks every second of staff time and generates billing reports for submission.
Standout Features
- Dual RPM/RTM platform—the only solution that monitors both physiological and non-physiological data
- Actuvi Intelligence with AI agents that automatically contact non-compliant patients via text/WhatsApp to provide reminders and administer assessments
- Flexible data collection: patients can sync data through Medical devices/Apple Health/Google Fit or log vitals directly in the app
- Guardian Access feature for patients who cannot use mobile apps independently
- Gamification with streaks and achievement metrics to maximize patient engagement
- Tracks staff time automatically and generates ready-to-submit reports
- White-glove onboarding: Actuvi designs your monitoring program, trains your team, and provides ongoing support
Best For
Practices seeking a comprehensive, scalable RPM solution that also supports RTM, with AI-powered patient engagement tools that maximize compliance without overwhelming clinical staff.
2. 100Plus
Website: https://www.100plus.com/
Why It Ranks
100Plus secures the #2 position with its RPM platform designed specifically for primary care practices. The platform focuses on chronic disease management for conditions like diabetes, hypertension, and congestive heart failure.
The platform’s care coordination features include automated patient outreach, medication adherence tracking, and integration with care management workflows. However, its focus on a narrower set of chronic conditions and lack of RTM capabilities compared to Actuvi’s multi-specialty versatility place it in the second position.
Best For
Primary care practices and ACOs focused on chronic disease management.
3. Cadence
Website: https://www.cadence.care/
Why It Ranks
Cadence ranks #3 with its patient-centric RPM platform that emphasizes user experience and engagement. The platform supports monitoring for cardiovascular conditions, diabetes, and respiratory diseases through partnerships with leading device manufacturers.
Cadence offers flexible device options, allowing practices to choose between cellular-enabled devices or Bluetooth devices that sync through the patient’s smartphone. While Cadence excels in patient engagement and offers solid device integration, it lacks Actuvi’s dual RPM/RTM capabilities and AI-powered patient engagement features, placing it in the middle of our rankings.
Best For
Practices prioritizing patient experience, particularly those serving tech-comfortable patient populations.
4. VitalTech
Website: https://www.vitaltech.io/
Why It Ranks
VitalTech earns the #4 spot with its RPM platform tailored for specialty practices, particularly cardiology and endocrinology. The platform offers deep integration with specialty-specific devices, including continuous glucose monitors (CGMs), cardiac event monitors, and advanced blood pressure cuffs with arrhythmia detection.
The platform’s strength lies in its sophisticated data analytics and reporting capabilities, which help specialists track complex patient conditions over time. However, its narrower focus on specialty care and higher price point compared to more versatile platforms like Actuvi limit its appeal to broader practice types. It’s ideal for specialty practices seeking advanced monitoring capabilities for complex conditions.
Best For
Cardiology and endocrinology practices managing complex chronic conditions requiring specialized monitoring devices.
5. Biobeat
Website: https://www.biobeat.com/
Why It Ranks
Biobeat earns the #5 position with its RPM platform centered on continuous monitoring technology using proprietary wearable patches and wrist devices. The platform’s strength lies in its ability to capture continuous physiological data streams for patients requiring intensive monitoring.
Biobeat’s continuous monitoring approach is particularly effective for high-acuity patients in post-operative recovery, heart failure management, or those requiring close observation between hospital visits. However, Biobeat’s reliance on proprietary wearable hardware creates barriers—patients must wear the device continuously, which can impact comfort and adherence. The platform is also significantly more expensive than traditional RPM solutions due to hardware costs.
Best For
Hospital systems and specialty practices managing high-acuity patients requiring continuous monitoring, particularly in post-acute care transitions and intensive chronic disease management.
Why Actuvi Stands Out
Actuvi’s top ranking stems from its unique position as the only platform that combines RPM and RTM capabilities in a single, integrated solution. This dual functionality means practices can monitor patients holistically—tracking both vital signs and patient-reported outcomes—without managing separate systems or workflows. The clinical benefits are significant: providers gain a complete picture of patient health, while patients experience a unified care journey through one mobile app.
From a financial perspective, Actuvi’s dual capability allows practices to maximize revenue by billing for RPM and RTM services (*note that the same patient can’t be billed for both at the same time). This, combined with Actuvi’s AI-powered patient engagement through Actuvi Intelligence, automated billing reports, and white-glove onboarding support, makes it the premier choice for 2025.
Unlike competitors that focus solely on RPM, Actuvi supports all specialties and all monitoring needs. Whether you’re a primary care practice managing diabetes, a pain clinic tracking therapeutic adherence, or a cardiology practice monitoring heart failure patients, Actuvi provides the tools, automation, and support to succeed. The platform’s AI agents ensure patient compliance without overwhelming staff, while the flexible data collection methods ensure equitable access for all patient populations.
For practices seeking a future-proof remote monitoring solution that combines both RPM and RTM, offers AI-driven patient engagement, and automates billing reports, Actuvi is the clear winner.
Learn more about Actuvi’s Remote Therapeutic Monitoring capabilities: Ranking the Best Remote Therapeutic Monitoring (RTM) Platforms
Final Thoughts
Choosing the right RPM platform depends on your practice’s specific needs—whether it’s Actuvi’s comprehensive dual RPM/RTM excellence with AI-powered engagement, 100Plus’s full-service chronic disease management, Cadence’s patient-centric design, VitalTech’s specialty-focused capabilities, or Biobeat’s wearable patch technology. As remote monitoring continues to transform healthcare delivery, these platforms lead the way in improving patient outcomes, reducing hospitalizations, and creating sustainable revenue streams.
For practices seeking the most versatile, revenue-enhancing, and clinically comprehensive remote monitoring solution, Actuvi is the definitive choice. Its unique ability to support both RPM and RTM within a single platform, combined with AI-powered patient engagement through Actuvi Intelligence, automated billing reports, and white-glove support, positions it as the market leader for 2025 and beyond.
